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Hospitals nationwide are seeking ways to use price transparency -- displaying the price of lab tests at the time when doctors are placing the order -- to nudge doctors to consider whether the benefits are worth the cost. But, results of a new study show that simply displaying the Medicare allowable fees did not have an overall impact on how clinicians ordered these tests. The results are published today in JAMA Internal Medicine and presented at the Society of General Internal Medicine annual meeting in Washington, DC.
Using the gene-editing tool CRISPR/Cas9, researchers at University of California San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health, with colleagues in China, have reprogrammed mutated rod photoreceptors to become functioning cone photoreceptors, reversing cellular degeneration and restoring visual function in two mouse models of retinitis pigmentosa.
The World Hepatitis Alliance today welcomes the publication of the first-ever Global Hepatitis Report by the World Health Organization (WHO), which includes new data on the prevalence and global burden of viral hepatitis.
Many companies want to know how the creation of their products affects the environment. Scientists at Stanford, the University of Minnesota and Unilever have found a way to better predict and quantify environmental impacts.
Results from a study presented today found that the incidence of HEV RNA in asymptomatic blood donors from Germany is higher than previously reported. The study, presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, showed that 0.11 percent of donations tested were HEV RNA positive and that one of the asymptomatic HEV RNA positive donors had previously donated HEV RNA positive blood products, which were then transfused into nine immunocompromised patients.
A new European study presented today demonstrated that patients with chronic HCV and severe liver damage, taken off the liver transplant list as a result of successful DAA therapy, had a favorable outcome over a year later. The study, presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, showed that 26.7 percent of patients could be removed from the waiting list due to clinical improvement.
A large epidemiological study presented today found that a diet high in animal protein was associated with a higher risk of non-alcoholic fatty liver disease (NAFLD), a condition in which fat builds up in the liver. These findings from The Rotterdam Study, presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, also showed that fructose consumption per se might not be as harmful as previously assumed.
A study presented today found that fecal transplantation of bacteria from one healthy donor into patients that suffer from hepatic encephalopathy, is safe and improves cognitive function compared with standard of care treatment for the condition. Presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, the study results also demonstrated that the number of hospitalizations following fecal transplantation plus antibiotics was two, compared to the standard of care arm, which was 11.
A study presented today that evaluated an investigational dosage of once-daily ledipasvir 45 mg/sofosbuvir 200 mg (LDV/SOF) in children aged six to 11 years infected with HCV, found that 99 percent of children had undetectable levels of HCV-RNA 12 weeks after treatment. The study, presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, showed that the fixed-dose combination of LDV/SOF was well-tolerated, and no patients experienced serious adverse events related to the study drug.
Study results presented today demonstrate that the oral, once-daily treatment regimen of glecaprevir/pibrentasvir resulted in 95 percent sustained virologic response rates 12 weeks post treatment in patients with HCV genotype 3. In the ENDURANCE-3 study, presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, patients infected with HCV genotype 3 without cirrhosis and who had no previous treatment history were treated with the new regimen for eight or 12 weeks, which was well tolerated.
Results from the CheckMate 040 study presented today found that nivolumab produces durable responses with long-term survival rates, regardless of whether or not patients were infected with Hepatitis B or C. Interim results from the study, presented at The International Liver Congress 2017 in Amsterdam, The Netherlands, showed that the overall objective response rate (ORR) was 14.5 percent and ORR by investigator assessment was 19.3 percent in sorafenib-experienced patients in the dose expansion phase of CheckMate 040.
New findings released today by Nemours Children's Health System show 64 percent of parents polled have used or plan to use telemedicine within the next year for their child. The survey, Telemedicine in America 2017: Parents Use of Virtual Visits, found that only 15 percent of parents have tried these services, but a strong majority is receptive to online doctor visits for common childhood ailments and routine well-child visits.
Plant biologists discovered for the first time on how factors arising from the mother and father in flowering plants cooperate to develop the shape of their child. Until now, it has been unknown whether paternal factors cooperate or conflict with each other to bring about zygote asymmetry. The outcome of this discovery is expected to shed light on the exact mechanism of plant body shape formation and possibly lead to the generation of new hybrid plants.
The BP oil spill in the Gulf of Mexico was the largest maritime oil spill in US history. Almost seven years to the day after the start of the environmental disaster, researchers have published a price tag of the damage done to natural resources: $17.2 billion.
Studies spanning the spectrum of cancer prevention and care, from immunotherapy and precision medicine to survivorship, will be highlighted in the official Press Program for the 53rd Annual Meeting of the American Society of Clinical Oncology (ASCO). Research results will be released in advance of and throughout the Annual Meeting, taking place June 2-6 in Chicago.
Honeybees -- employed to pollinate crops during the blooming season -- encounter danger due to lingering and wandering pesticides, according to a new Cornell University study that analyzed the bee's own food.
The American Society of Mass Spectrometry has named Saiful Chowdhury, assistant professor of chemistry and biochemistry at The University of Texas at Arlington, as one of the leading emerging investigators worldwide for his work developing new techniques using mass spectrometry to differentiate protein modifications linked to cancer and aging.
People with multiple sclerosis can show signs of something wrong five years before the onset of disease, much earlier than previously thought, according to a new analysis of health records from people with the condition.
New research suggests that some firms manipulate the content and tone of their company reports despite an initiative to make them more concise and balanced.The study, led by Dr Gaia Melloni at the University of East Anglia (UEA), examined a sample of firms involved in a pilot programme to produce integrated reports. These combine usually separate financial and sustainability -- environmental, social and governance -- details of a company's performance.
Study examines use of psychoactive drugs to enhance cognition, creativity, and pleasure.