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Seeing small-molecule interactions inside cells (video)

EurekAlert! - Mar, 12/11/2018 - 23:00
Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs that cause specific proteins to associate more or less with their 'coworkers.' Now, researchers reporting in ACS' journal Analytical Chemistry have developed a method to visualize whether drugs are regulating protein-protein interactions inside cells.

Fallen through the net?

EurekAlert! - Mar, 12/11/2018 - 23:00
Using long-term data from the "Butterfly Monitoring Germany" citizens' research project, scientists have now investigated the matter using butterflies as an example. According to the research, there are more butterfly species in Natura 2000 areas than elsewhere. However, the same decline in the numbers of species regardless whether the communities are located within or outside the protected areas.

An intellectually active lifestyle protects against neurodegeneration in Huntington's

EurekAlert! - Mar, 12/11/2018 - 23:00
Researchers from IDIBELL and the University of Barcelona (UB), in collaboration with several hospitals, have discovered that an intellectually active lifestyle confers protection against neurodegeneration in people with Huntington's disease, delaying the onset of symptoms and loss of grey matter in the brain.

Scientists develop a cellulose biosensor material for advanced tissue engineering

EurekAlert! - Mar, 12/11/2018 - 23:00
I.M. Sechenov First Moscow State Medical University teamed up together with Irish colleagues to develop a new imaging approach for tissue engineering. The team produced so-called 'hybrid biosensor' scaffold materials, which are based on cellulose matrices labeled with pH- and calcium-sensitive fluorescent proteins. These materials enable visualization of the metabolism and other important biomarkers in the engineered artificial tissues by microscopy.

Tube travel linked to the spread of flu-like illnesses

EurekAlert! - Mar, 12/11/2018 - 23:00
Despite the commuter cold being a widely accepted concept, it has never been proven that public transport contributes to the spread of airborne infections. Now new research on the London underground commute has proven a link does exist.

New transport mechanism of nanomaterial through a cell membrane: membrane stretching

EurekAlert! - Mar, 12/11/2018 - 23:00
The team of theoretical physics at Universitat Rovira i Virgili in Tarragona, led by Dr. Vladimir Baulin, designed a research project to investigate the interaction between nanotube and lipid membranes. The researchers studied what they call a 'model bilayer', composed only by one type of lipid, and they observed that it is possible to control the transport of nanomaterial across a cell membrane by tuning the membrane tension.

Pitt chemical engineers advance olefins production through computational modeling

EurekAlert! - Mar, 12/11/2018 - 23:00
New research from the University of Pittsburgh's Swanson School of Engineering has introduced a method to effectively screen different catalysts that convert light alkanes to olefins. With light alkanes being abundant in the Marcellus and Utica shale reserves, this methodology may provide a more economical solution for olefins production.

Chickens to be marker of Anthropocene

EurekAlert! - Mar, 12/11/2018 - 23:00
New research shows the age of man -- the Anthropocene -- will be defined by the chicken.

Lung lavage as new test method improves tuberculosis diagnosis in rhinoceros

EurekAlert! - Mar, 12/11/2018 - 23:00
An international team of scientists led by institutes in Berlin and Jena, Germany, performed repeated lung lavage as a new approach for tuberculosis diagnosis in rhinoceros. Subsequent genetic tests reliably identified mycobacteria in the animals' respiratory fluids -- with minimal stress and risk for the rhinos. The study has been published in the journal PLOS ONE.

New research questions the 'Glass Cliff' and corroborates the persistent 'Glass Ceiling'

EurekAlert! - Mar, 12/11/2018 - 23:00
Are women more likely to be appointed to leadership positions in crisis situations when companies are struggling with declining profits?

New insight into stem cell behavior 'highlights therapeutic target for cancer treatment'

EurekAlert! - Mar, 12/11/2018 - 23:00
Research led by the University of Plymouth and Technische Universität Dresden has identified a new therapeutic target for cancer treatment and tooth regeneration -- a protein called Prominin-1.

Record-wet and record-dry months increased in regions worldwide

EurekAlert! - Mar, 12/11/2018 - 23:00
More and more rainfall extremes are observed in regions around the globe -- triggering both wet and dry records, a new study shows. Yet there are big differences between regions: The central and Eastern US, northern Europe and northern Asia have experienced heavy rainfall events that have led to severe floods in recent past. In contrast, most African regions have seen an increased frequency of months with a lack of rain.

Insight into cause of rare disorder may aid quest for treatments

EurekAlert! - Mar, 12/11/2018 - 23:00
New findings about the causes of a rare genetic disorder that affects mainly boys, known as MeCP2 duplication syndrome, may inform the development of treatments for the condition.

Obtaining polyester from plant oil

EurekAlert! - Mar, 12/11/2018 - 23:00
University of Konstanz chemist Professor Stefan Mecking publishes a new catalysis concept for obtaining polyester from castor oil.

More 'heatwave' summers will affect animals

EurekAlert! - Mar, 12/11/2018 - 23:00
Heatwaves similar to those experienced in Europe in 2018 can have a very negative impact on animals. A new study from Lund University in Sweden shows that overheated birds have smaller offspring, and that those that are born may have lower chances of survival.

Mini-detectors for the gigantic?

EurekAlert! - Mar, 12/11/2018 - 23:00
The gravitational waves created in the depths of space indeed reach Earth. Their effects, however, are so small that they could only be observed so far using kilometer-long measurement facilities. Physicists therefore discuss whether Bose-Einstein condensates with their ordered quantum properties could also detect these waves. Prof. Ralf Schützhold from HZDR and TU Dresden has now looked at these suggestions and has soberly determined that such evidence is far beyond the reach of current methods.

How bullying affects the brain

EurekAlert! - Mar, 12/11/2018 - 23:00
The effects of constantly being bullied are more than just psychological. Research now shows that there may be physical structural differences in the brains of adolescents who are regularly victimized, and this could increase the chance that they suffer from mental illness.

SFU scientists automated electrolyte composition analysis for aluminium production

EurekAlert! - Mar, 12/11/2018 - 23:00
A team from Siberian Federal University (SFU) suggested a new method for automatic composition analysis of electrolyte samples from electrolysis baths. It will provide for more accurate technological control and increase the efficiency of aluminium production. The article of the scientists was published in the Crystals journal.

New method for studying ALS more effectively

EurekAlert! - Mar, 12/11/2018 - 23:00
The neurodegenerative disease ALS causes motor neuron death and paralysis. However, long before the cells die, they lose contact with the muscles as their axons atrophy. Researchers at Karolinska Institutet in Sweden have now devised a new method that radically improves the ability to study axons and thus to better understand the pathological development of ALS.

University of Miami medical team reports acute findings from Havana embassy phenomenon

EurekAlert! - Mar, 12/11/2018 - 23:00
A team of University of Miami Miller School of Medicine faculty, along with collaborators from the University of Pittsburgh, today presented the first report of acute symptoms and clinical findings in 25 diplomatic personnel living in the US Embassy in Havana, Cuba, who experienced severe neurosensory symptoms after exposure to a unique sound and pressure phenomenon.

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