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Review reveals potential predictors of long-term distress after cancer diagnosis

Mar, 01/09/2018 - 23:00
A new review of published studies indicates that distress and neuroticism at or within three months of cancer diagnosis may predict emotional distress at least 12 months later. In the Psycho-Oncology analysis, there was no consistent evidence that demographic, clinical, or social factors reliably predict long-term distress.

Endometriosis may increase the risk of bladder pain syndrome/interstitial cystitis

Mar, 01/09/2018 - 23:00
A new Neurology & Urodynamics study has demonstrated a link between endometriosis and a subsequent diagnosis of bladder pain syndrome/interstitial cystitis (BPS/IC).

Ethical issues are important in 'standard-of-care' clinical trials

Mar, 01/09/2018 - 23:00
A learning healthcare system (LHS) aligns science, informatics, incentives, and culture for continuous improvement and innovation, with a delivery process that is based on best practices while also capturing new knowledge. Integral to LHSs are clinical trials that compare interventions that are already commonly in use (as 'accepted' or 'standard-of-care').

Study examines urinary tract infections and antibiotic use in nursing homes

Mar, 01/09/2018 - 23:00
In a Journal of the American Geriatrics Society study of nursing homes in the tropics, one in five residents had received antibiotics within the last 30 days. Also, urinary tract infection (UTI) accounted for 40 percent of all infections treated with antibiotics within the last 30 days.

Study provides insights on links between childhood abuse and later depression

Mar, 01/09/2018 - 23:00
Results from an International Journal of Geriatric Psychiatry study suggest that smaller social networks and feelings of loneliness might be important risk factors for late-life depression in older adults with a history of childhood abuse as well as with an earlier onset of depression.

Research may improve artificial joints used in hip replacement surgery

Mar, 01/09/2018 - 23:00
A new Journal of Orthopaedic Research study that examined artificial joints used for total hip replacement found that ceramic components may experience less corrosion than cobalt-chromium components.

Analysis examines link between bone turnover markers and fracture risk in osteoporosis trials

Mar, 01/09/2018 - 23:00
Pooled data from 14 osteoporosis clinical trials of anti-resorptive drugs indicate that patients who have reduced levels of two bone turnover markers during treatment have lower risks of later experiencing vertebral fractures. No bone turnover markers were significantly associated with non-vertebral or hip fracture risks, according to the Journal of Bone and Mineral Research analysis.

Could melatonin be the key to healthy aging?

Mar, 01/09/2018 - 23:00
A new British Journal of Pharmacology review highlights the role of melatonin -- a hormone that is produced at night -- in regulating sleep and the body's biological, or circadian, clock. Research suggests that melatonin treatments may even help to improve the restorative value of sleep and to promote healthy physical and mental aging.

Certain factors may predict lung cancer patients' response to chemotherapy

Mar, 01/09/2018 - 23:00
In a retrospective analysis of 73 lung squamous cell carcinoma patients treated with the chemotherapy regimen of gemcitabine plus cisplatin, higher body mass index and younger age were linked with longer progression-free survival, the length of time that a patient lives with cancer but it does not get worse. Patients with better response to treatment and higher body mass index had longer overall survival in the Thoracic Cancer analysis.

Engineered sandbars don't measure up for nesting plovers

Mar, 01/09/2018 - 23:00
Dams reduce the creation of natural sandbars, which is bad news for birds that depend on them for nesting habitat. More than 200 hectares of engineered sandbars have been built along the Missouri River to address this problem -- but how does this compare to the real thing? A new study takes advantage of a natural experiment created by the region's 2011 floods, demonstrating that engineered habitat doesn't provide the benefits of sandbars created by nature.